Here are some one liners...
Tacky's War... A Change in Attitude Toward Slavery -- A slave rebellion will cause British planters to shy away from imported slaves and focus on encouraging current female slaves to have children who will then become slaves.
The First and the Oldest American Tobacco Company -- It had to start sometime. I talk about how the CEO actually tried to convince Congress that nicotine was not addictive and that cigarettes did not cause cancer.
Mad King George the 3rd Takes the Throne -- He is not mad yet and he will make a reasonable King, but he will be on the throne for the American Revolution, so from an American perspective he is see in a poor light.